3,4-dichloroaniline

Additional ecotoxological information

Administrative data

Endpoint:

additional ecotoxicological information

Type of information:

experimental study

Adequacy of study:

other information

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: only results in EU risk assessment

Data source

Reference

Reference 1

Reference Type:

publication

Title:

Toxikokinetik von 3,4-Dichloranilin beim dreistachligen Stichling (Gasterosteus aculeatus) unter besonderer Berücksichtigung der Fortpflanzungsphysiologie.

Author:

Allner B (1997)

Year:

1997

Bibliographic source:

Dissertation am Fachbereich Biologie der Johann Gutenberg-Universität in Mainz.

Reference 2

Reference Type:

secondary source

Title:

3,4-dichloroaniline (3,4-DCA)

Author:

EU-Risk Assessment Report

Year:

2006

Bibliographic source:

EUR 22235 EN; ISSN 1018-5593

Materials and methods

Test guideline

Qualifier:

no guideline available

Principles of method if other than guideline:

no data

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

3,4-dichloroaniline

EC Number:

202-448-4

EC Name:

3,4-dichloroaniline

Cas Number:

95-76-1

Molecular formula:

C6H5Cl2N

IUPAC Name:

3,4-dichloroaniline

Results and discussion

Any other information on results incl. tables

3,4-DCA is known to have endocrine effects on fish. It could be shown (Allner, 1997) that 3,4-DCA causes lowered androgen synthesis at tested concentrations of 200 and 400 µg/l in breeding male Sticklebacks (Gasterosteus aculeatus). The changes in androgen metabolism are accompanied by changes in the secondary sex characters at concentration of 100, 200 und 400 µg/l. The splendid colour typical of breeding males become regressive and courtship behavior occurs no longer.