Registration Dossier
Registration Dossier
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EC number: 202-448-4 | CAS number: 95-76-1
Sediment toxicity
Administrative data
- Endpoint:
- sediment toxicity: long-term
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Original paper not available but peer reviewed in EU Risk assessment.
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- 3,4-dichloroaniline (3,4-DCA)
- Author:
- EU-Risk Assessment Report
- Year:
- 2 006
- Bibliographic source:
- EUR 22235 EN; ISSN 1018-5593
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 000
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Long term test with Lumbriculus variegatus.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3,4-dichloroaniline
- EC Number:
- 202-448-4
- EC Name:
- 3,4-dichloroaniline
- Cas Number:
- 95-76-1
- Molecular formula:
- C6H5Cl2N
- IUPAC Name:
- 3,4-dichloroaniline
Constituent 1
Test organisms
- Test organisms (species):
- Lumbriculus variegatus
Study design
- Study type:
- laboratory study
- Test type:
- not specified
- Water media type:
- freshwater
- Type of sediment:
- artificial sediment
- Limit test:
- no
Exposure duration
- Duration:
- 28 d
- Exposure phase:
- total exposure duration
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 25.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 5 mg/kg sediment dw
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Duration:
- 14 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 25 mg/kg sediment dw
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
Any other information on results incl. tables
For Lumbriculus variegatus a NOEC of 5 mg/kg dw was found for the total number of worms. This can be seen as the endpoint
relevant for the assessment.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
