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Ecotoxicological information

Long-term toxicity to fish

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Reference
Endpoint:
adult fish: sub(lethal) effects
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
Data is from computational model developed by USEPA
Qualifier:
according to
Guideline:
other: Modelling database
Principles of method if other than guideline:
To study the effect of test chemical on fish using the predicted data from ECOSAR v1.1
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
other: Fish
Test type:
flow-through
Water media type:
freshwater
Total exposure duration:
28 d
Reference substance (positive control):
not specified
Key result
Duration:
28 d
Dose descriptor:
NOEC
Effect conc.:
2.587 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
mortality
Validity criteria fulfilled:
no
Conclusions:
The 28 days chronic toxicity to fish was predicted by using the ECOSAR 1.11 version. The predicted NOEC value for test chemical was 2.587 mg/L.
Executive summary:

The 28 days chronic toxicity to fish was predicted by using the ECOSAR 1.11 version. The predicted NOEC value for test chemical was 2.587 mg/L. This NOEC suggests that test chemical could not exhibit long term toxicity to fish and thus can be considered to not classified according to CLP criteria.

Description of key information

The 28 days chronic toxicity to fish (ChV) was predicted by using the ECOSAR 1.11 version. The predicted ChV value for test chemical was 2.587 mg/L..

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
2.587 mg/L

Additional information

The 28 days chronic toxicity to fish was predicted by using the ECOSAR 1.11 version. The predicted NOEC value for test chemical was 2.587 mg/L. This NOEC suggests that test chemical could not exhibit long term toxicity to fish and thus can be considered to not classified according to CLP criteria.