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EC number: 203-412-0 | CAS number: 106-58-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Oxidising properties
Administrative data
Link to relevant study record(s)
- Endpoint:
- oxidising liquids
- Type of information:
- other: Expert statement
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Expert statement
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.21 (Oxidising Properties (Liquids))
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Dimethyl Piperazine
- Substance type: Clear liquid
- Physical state: Liquid
- Lot/batch No.: 1903-3/2012 - Sample tested:
- other: not tested/measured
- Remarks:
- but based on expert statement
- Parameter:
- other: examination of structural formula of the test substance
- Remarks on result:
- other: The structure does not comprise any functional group related to oxidising properties or electronegative atoms
- Remarks:
- Hence the test item is not expected to exhibit oxidising properties
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- On the basis of this exercise, the material should be considered as not oxidising and should not be subjected to experimental testing. The material meets all criteria for exemption from testing and has a structure not at all conducive with that required to exhibit oxidising tendencies.
- Endpoint:
- oxidising liquids
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and hence, the classification procedure does not need to be applied
- the study does not need to be conducted because the organic substance does not contain oxygen or halogen atoms and hence, the classification procedure does not need to be applied
Referenceopen allclose all
Examining the structural formula, the following observations can be made:
- The molecule does not contain any functional groups such as organic nitro compounds, N-halogen compounds (N-X), Oxohalogen compounds, interhalogen compounds
- The highly electronegative atoms which are present constitute a high proportion of the molecule and are bound to elements in a high oxidation state. In case of dimethyl piperazine there are no highly electronegative atoms
- The highly electronegative atoms which are bonded to each other or to other electronegative elements such as iodine, nitrogen, sulphur or phosphorus. In the case of dimethyl piperazine, there are no highly electronegative atoms.
- Assessment against the above criteria indicates strongly that the molecule will not have oxidising properties.
In every aspect of the oxidising liquids exemption procedure, dimethyl piperazine does not show any evidence of possessing oxidising properties.
Description of key information
Based on the chemical structure, the test substance is determined to be non-oxidising (waiver statement). This conclusion is supported by a theoretical expert assessment (Younis, 2013).
Key value for chemical safety assessment
- Oxidising properties:
- non oxidising
Additional information
Justification for classification or non-classification
1,4-dimethyl piperazine does not need to be classified as an oxidising substance as based on the chemical structure the substance does not contain any chemical groups indicating oxidising properties. The substance also does not contain any oxygen or halogen atoms, and therefore the classification procedure does not need to be applied.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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