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Oxidising properties

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Endpoint:
oxidising liquids
Type of information:
other: Expert statement
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Expert statement
Qualifier:
according to guideline
Guideline:
EU Method A.21 (Oxidising Properties (Liquids))
Deviations:
no
GLP compliance:
yes
Specific details on test material used for the study:
- Name of test material (as cited in study report): Dimethyl Piperazine
- Substance type: Clear liquid
- Physical state: Liquid
- Lot/batch No.: 1903-3/2012
Sample tested:
other: not tested/measured
Remarks:
but based on expert statement
Parameter:
other: examination of structural formula of the test substance
Remarks on result:
other: The structure does not comprise any functional group related to oxidising properties or electronegative atoms
Remarks:
Hence the test item is not expected to exhibit oxidising properties

Examining the structural formula, the following observations can be made:

- The molecule does not contain any functional groups such as organic nitro compounds, N-halogen compounds (N-X), Oxohalogen compounds, interhalogen compounds

- The highly electronegative atoms which are present constitute a high proportion of the molecule and are bound to elements in a high oxidation state. In case of dimethyl piperazine there are no highly electronegative atoms

- The highly electronegative atoms which are bonded to each other or to other electronegative elements such as iodine, nitrogen, sulphur or phosphorus. In the case of dimethyl piperazine, there are no highly electronegative atoms.

- Assessment against the above criteria indicates strongly that the molecule will not have oxidising properties.

In every aspect of the oxidising liquids exemption procedure, dimethyl piperazine does not show any evidence of possessing oxidising properties.

Interpretation of results:
GHS criteria not met
Conclusions:
On the basis of this exercise, the material should be considered as not oxidising and should not be subjected to experimental testing. The material meets all criteria for exemption from testing and has a structure not at all conducive with that required to exhibit oxidising tendencies.
Endpoint:
oxidising liquids
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and hence, the classification procedure does not need to be applied
the study does not need to be conducted because the organic substance does not contain oxygen or halogen atoms and hence, the classification procedure does not need to be applied

Description of key information

Based on the chemical structure, the test substance is determined to be non-oxidising (waiver statement). This conclusion is supported by a theoretical expert assessment (Younis, 2013).

Key value for chemical safety assessment

Oxidising properties:
non oxidising

Additional information

Justification for classification or non-classification

1,4-dimethyl piperazine does not need to be classified as an oxidising substance as based on the chemical structure the substance does not contain any chemical groups indicating oxidising properties. The substance also does not contain any oxygen or halogen atoms, and therefore the classification procedure does not need to be applied.