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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Data is from secondary source, authoritative and modelling databases
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
Estimation of octanol water partition coefficient of the test chemical.
GLP compliance:
not specified
Type of method:
other: no data available
Partition coefficient type:
octanol-water
Key result
Type:
log Pow
Partition coefficient:
-1.39
Remarks on result:
other: Other details not known
Details on results:
The logKow of test chemical was estimated to be -1.39.
Conclusions:
The partition coefficient (log Pow) value of the test chemical was estimated to be -1.39.
Executive summary:

The partition coefficient (log Pow) value of the test chemical was estimated to be -1.39. Based on this value, test chemical can be considered to be hydrophilic in nature.

Description of key information

Based on the available data from authoritative and modelling databases,the partition coefficient (log Pow) value of the test chemical was estimated to be -1.39. On the basis of this value, test chemical can be considered to be hydrophilic in nature.

Key value for chemical safety assessment

Log Kow (Log Pow):
-1.39

Additional information

Based on the available data in a key study from authoritative and modelling databases, the partition coefficient (log Pow) value of the test chemical was estimated to be -1.39.

In a supportingstudy from handbook, the partition coefficient (log Pow) value of the test chemical was estimated to be -0.4.

Additional study from modelling database indicates that the octanol water partition coefficient (log Pow) value of the test chemical was estimated to be -1.46 ± 1.07.

Thus, based on the available information, the logPow valueof the test chemical ranges from -1.46 to -0.4, respectively. On the basis of this value, test chemical can be considered to behydrophilic in nature.