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Toxicological information

Specific investigations: other studies

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Administrative data

Endpoint:
biochemical or cellular interactions
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: This information was obtained from the public IUCLID 2000 CD-ROM. The original report has not been reviewed further. Assessment of data quality to current OECD standards is not possible and the study has therefore been assigned Reliability 4.

Data source

Reference
Reference Type:
publication
Title:
Further studies on the ability of different metal salts to influence the DNA synthesis of human lymphoid cells.
Author:
Nordlind K
Year:
1986
Bibliographic source:
PMID 3941015 Int Archs Allergy Appl Immun 79(1):83-5.

Materials and methods

Endpoint addressed:
genetic toxicity

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Details on results:
On the thymocytes ferric chloride gave a slight stimulation at 1.2 × 10^–3M. Thus, the tested metal salts should be suitable for use in lymphocyte transformation tests for diagnosis of contact allergy.

Applicant's summary and conclusion