Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Specific investigations: other studies

Currently viewing:

Administrative data

biochemical or cellular interactions
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
supporting study
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: This information was obtained from the public IUCLID 2000 CD-ROM. The original report has not been reviewed further. Assessment of data quality to current OECD standards is not possible and the study has therefore been assigned Reliability 4.

Data source

Reference Type:
Further studies on the ability of different metal salts to influence the DNA synthesis of human lymphoid cells.
Nordlind K
Bibliographic source:
PMID 3941015 Int Archs Allergy Appl Immun 79(1):83-5.

Materials and methods

Endpoint addressed:
genetic toxicity

Test material

Constituent 1
Chemical structure
Reference substance name:
Iron trichloride
EC Number:
EC Name:
Iron trichloride
Cas Number:
Molecular formula:
iron(3+) trichloride

Results and discussion

Details on results:
On the thymocytes ferric chloride gave a slight stimulation at 1.2 × 10^–3M. Thus, the tested metal salts should be suitable for use in lymphocyte transformation tests for diagnosis of contact allergy.

Applicant's summary and conclusion