Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 401-100-0 | CAS number: 109037-78-7 TILCOM CA35; TILCOM IA10; TYTAN AP 100; TYTAN CA 100; TYTAN CX 35; TYZOR IAM
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
- Year:
- 2 014
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Annex V
- GLP compliance:
- yes
Test material
- Reference substance name:
- Butyl (dialkyloxy(dibutoxyphosphoryloxy))titanium(trialkyloxy)titanium phosphate
- EC Number:
- 401-100-0
- EC Name:
- Butyl (dialkyloxy(dibutoxyphosphoryloxy))titanium(trialkyloxy)titanium phosphate
- Cas Number:
- 109037-78-7
- Molecular formula:
- not applicable
- IUPAC Name:
- dititanium(4+) triethanolate bis(propan-1-olate) dibutyl phosphate butyl phosphate
Constituent 1
Test animals
- Species:
- rabbit
Test system
- Type of coverage:
- semiocclusive
- Duration of treatment / exposure:
- 4 hours
- Number of animals:
- 3
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- erythema score
- Basis:
- animal #1
- Time point:
- 24/48/72 h
- Score:
- ca. 0
- Max. score:
- 1
- Reversibility:
- other: summary provided by ECHA 2014
- Remarks:
- Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Remarks on result:
- other: Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Remarks:
- Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Irritation parameter:
- erythema score
- Basis:
- animal #2
- Time point:
- 24/48/72 h
- Score:
- ca. 0.3
- Max. score:
- 2
- Reversibility:
- other: summary provided by ECHA 2014
- Remarks:
- Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Remarks on result:
- other: Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Remarks:
- Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Irritation parameter:
- erythema score
- Basis:
- animal #3
- Time point:
- 24/48/72 h
- Score:
- ca. 0
- Max. score:
- 3
- Reversibility:
- other: summary provided by ECHA 2014
- Remarks:
- Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Remarks on result:
- other: Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Remarks:
- Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Irritation parameter:
- edema score
- Basis:
- animal #1
- Time point:
- 24/48/72 h
- Score:
- ca. 1
- Max. score:
- 1
- Reversibility:
- other: summary provided by ECHA 2014
- Remarks:
- Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Remarks on result:
- other: Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Remarks:
- Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Irritation parameter:
- edema score
- Basis:
- animal #2
- Time point:
- 24/48/72 h
- Score:
- ca. 1
- Max. score:
- 1
- Reversibility:
- other: summary provided by ECHA 2014
- Remarks:
- Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Remarks on result:
- other: Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Remarks:
- Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Irritation parameter:
- edema score
- Basis:
- animal #3
- Time point:
- 24/48/72 h
- Score:
- ca. 1
- Max. score:
- 1
- Reversibility:
- other: summary provided by ECHA 2014
- Remarks:
- Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Remarks on result:
- other: Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Remarks:
- Information from migrated NONS file, as per inquiry number 06-2120053135-66-0000, permission to refer granted by ECHA
- Irritant / corrosive response data:
- not classified as irritant
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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