Registration Dossier

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

Three in vitro genetic toxicity studies were conducted on FBSEE diol. The results of the studies were:

 

Chromosome aberration: Negative with and without metabolic activation when tested according to OECD 473 (1997).

 

Ames assay: Negative with and without metabolic activation when tested according to OECD 471 (1997).

 

Mouse Lymphoma assay: Negative with and without metabolic activation when tested according to OECD 490 (2016).

Additional information

Justification for classification or non-classification

Based on the results of the studies, FBSEE diol does not meet the classification criteria for genotoxicity.