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EC number: 946-101-1
CAS number: -
on the oral LD50 >2000 mg/kg bw, the test substance is not considered to
be harmful or toxic by oral or dermal routes.
study was conducted to determine the acute oral toxicity of the test
substance according to OECD guideline 423 and EPA OPPTS 870.1100 (acute
toxic class method), in compliance with GLP. The test substance was
administered by gavage to two consecutive groups of three female Wistar
rats at a concentration of 2000 mg/kg bw. Animals were subjected to
daily observation and weekly determination of body weight. Macroscopic
examination was performed after terminal sacrifice on Day 15. No
mortality occurred. Hunched posture and/or piloerection were noted for
three animals on Day 1 only. The mean body weight gain over the study
period was considered to be normal. Finally, no abnormalities were found
at macroscopic post mortem examination. Under the study conditions, the
rat oral LD50 for the test substance was considered to exceed 2000 mg/kg
bw (van Huygevoort, 2016).
on the results of an acute oral toxicity study, the test substance does
not meet the criteria for classification for this endpoint according to
CLP (Regulation 1272/2008/EC) criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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