Registration Dossier
Registration Dossier
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EC number: 946-101-1 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Based on the results of the read across study, the 3h EC50 and NOEC of the test substance were determined to be >1000 mg/L and 1000 mg/L, respectively.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
A study was conducted to determine the toxicity of the read across substance, 1-octadecanol, phosphate, potassium salt (i.e., mono- and di- C18 PSE, K+) to microorganisms according OECD guideline 209 and EU Method C.11 (Activated Sludge, Respiration Inhibition Test), in compliance with GLP. Activated sludge of a predominantly domestic sewage was exposed to the test substance at nominal concentrations of 0, 1.4, 10.6, 99.4 and 1000 mg/L for 3 h. A positive control (3,5 -dichlorophenol) was included in the experiment. At the highest test substance concentration 1000 mg/L, no statistically significant inhibition could be observed. Therefore, based on the results of the read across study, the 3h EC50 and NOEC of the test substance were determined to be >1000 mg/L and 1000 mg/L, respectively (Muckle, 2012).
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