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EC number: 271-089-3
CAS number: 68515-47-9
Long-term toxicity to aquatic invertebrates:Conclusion: Results of two studies show that DTDP will not produce chronic toxicity to invertebrates at or below its maximum attainable water solubility.
results of long-term toxicity studies are reported as EC50and
NOEC values for chronic invertebrate toxicity. The NOEC values represent
the highest concentration measured in these studies that did not
demonstrate effects. In all cases this was the highest concentration
attainable and measured under the conditions of the study. The use of
the NOEC values in the results overview table to derive values for
quantitative risk assessment is inappropriate as they are not true NOEC
Results from long-term toxicity
studies with an invertebrate show
that DTDP does not cause chronic toxicity at the maximum
achievable aqueous concentrations investigated in these tests (i.e. in
excess of water solubility). The studies tested DTDP up to its
solubility limit under the conditions of the studies. In
comparison, the Brownet al.(1998) study used a surfactant to
achieve an exposure solution with a stable emulsion of DTDP at a level
that far exceeded its water solubility. The use of a surfactant in
comparison to the study that did not use a surfactant explains the large
difference in the reported EC50and NOEC values.
The data used to characterize the
invertebrate chronic toxicity of di-isotridecyl phthalate (DTDP) ester
are consistent with the data for several high molecular weight phthalate
diesters summarized by Staples et al. (1997). These data show that high
molecular weight phthalate diesters do not produce chronic toxicity to
invertebrates at or below their maximum attainable solubliity. The acute
invertebrate dataset includes results for one species, Daphnia magna.
Staples et al. (1997). Aquatic toxicity of
eighteen phthalate esters. Environ. Toxicol. Chem. 16(5): 875 -891.
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