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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Mildly irritating to skin with prolonged exposure. Based on test data for the material.
May cause mild, short-lasting discomfort to eyes. Based on test data for the material.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Acute skin irritation studies with DTDP have been conducted in both humans and rabbits (ExxonMobil, 1981; 1995; Sasol, 1984).  In laboratory animals, DTDP is at most slightly irritating to the skin and eye and the effects are fully reversible in a relatively short period of time. In human studies, there are no indications DTDP produces skin irritation. These results are similar to the results observed with other high molecular weight phthalate esters. Respiratory tract irritation has not been reported in humans. Based on these observations, DTDP is not considered irritating or corrosive.

Justification for classification or non-classification

No classification for skin/eye irritation or corrosion is indicated according to the general classification and labeling requirements for dangerous substances and preparations (Directive 67-548-EEC) or the classification, labeling and packaging (CLP) regulation (EC) No 1272/2008.