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EC number: 203-838-7
CAS number: 111-14-8
Biodegradation in water: screening tests: Readily Biodegradable: 94.5% and 98.7 % biodegradation (DOC removal) after 4 and 11 days, respectively. The 10-days window was met (OECD TG 301 A: Ready Biodegradability: DOC Die Away Test) - (EU Method C.4-A: Determination of the "Ready" Biodegradability - DOC Die-Away Test).
One key study (VOELSKOW H., 1996) is available for this endpoint.
This study has been performed in accordance with the OECD Guideline
(Ready Biodegradability: DOC Die Away Test) and the EU Directive
92/69/EEC C.4-A (Determination of the "Ready" Biodegradability - DOC
Die-Away Test) and in compliance with the Good Laboratory Practice
standards. The study showed a level of biodegradation of 94.4 and 98.7 %
(DOC removal) after 4 and 11 days, respectively. The 10 -d window was
met. Based on these results, Heptanoic acid is considered as readily
biodegradable. Among the 3 validity criteria (OECD TG 301D), one was
fulfilled and the others could not have been checked due to lack of raw
data. Consequently, the study is considered as reliable with
A second study is available (DIAS F.F. & ALEXANDER M., 1971)
focusing on the determination of the Biochemical Oxygen Demand (BOD).
The BOD determination alone cannot be considered as a valid
determination of the biodegradability of a substance. However, using a
calculated Theoretical Oxygen Demand, a percentage of biodegradation can
be deduced from the measured BOD. Applying this approach, Heptanoic acid
reached 44, 61, 54 and 58% of its theoretical BOD after 2, 5, 10 and 30
days, respectively, showing a potential of biodegradation. Therefore,
this study is considered as supporting the results of the key study.
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