Registration Dossier
Registration Dossier
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EC number: 220-877-5 | CAS number: 2923-16-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
By analogy with TFANa, the 96h LC50 of TFAK is >1200 mg/L.
Key value for chemical safety assessment
Additional information
No data on potassium trifluoroacetate is available for this endpoint. However, a reliable key study is available for sodium trifluoroacetate which is used in a read-across approach. The results expressed in TFANa is directly applied to TFAK in a worst case approach (i.e. the molecular weight of Na is lower than the molecular weight of K).
In this 96-h acute toxicity study, performed under static conditions following the OECD Guideline 203, Zebrafish (Danio rerio, n=10) were exposed in a limit test at 1200 and 0 mg/l of sodium trifluoroacetate in duplicate. No mortality was observed resulting in a LC50(96h) > 1200 mg/l and NOEC = 1200 mg/l of TFANa. All validity criteria were fulfilled, i.e. mortality in fish control < 10%, constant conditions were maintained throughout the test, dissolved oxygen concentration was >= 60% of the air saturation value throughout the test, and tested concentration has been maintained for at least 80% of the nominal concentration throughout the test.
By analogy, potassium trifluoroacetate is considered as not harmful to fish.
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