Registration Dossier

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study obtained through inquiry process; SNIF file obtained from ECHA.

Data source

Reference
Reference Type:
other: SNIF
Title:
Unnamed
Year:
1997

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method C.1 (Acute Toxicity for Fish)
Deviations:
not specified
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
not specified

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)

Study design

Test type:
static
Water media type:
freshwater
Total exposure duration:
96 h

Test conditions

Hardness:
250 mg CaCO3/L
Reference substance (positive control):
not specified

Results and discussion

Effect concentrationsopen allclose all
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 0.21 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
mortality
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
> 0.21 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
mortality
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
> 0.21 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
not specified
Details on results:
%Concentration loss over test: 40 ...
No effects noted at above the level of water solubility.

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
LC50 (96h) > 0.21 mg/L
LC100 (96h) > 0.21 mg/L
NOEC (96h) > 0.21 mg/L;
Due to its very low water solubility (see IUCLID section 4.8), the test substance is considered not to be toxic to fish under the conditions of the test.
Executive summary:

The acute toxicity of the test substance to fish has been determined in a static test with zebra fish (Brachydanio rerio) according to EU Method C.1. The LC50 (96h), the LC100 (96h) and the NOEC (96h) were > 0.21 mg/L. No mortality and no effects were observed in the range of the low water solubility of the test substance. Therefore, the test substance is considered not to be harmful to fish.