Registration Dossier
Registration Dossier
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EC number: 422-600-5 | CAS number: 73936-91-1
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study obtained through inquiry process; SNIF file obtained from ECHA.
Data source
Reference
- Reference Type:
- other: SNIF
- Title:
- Unnamed
- Year:
- 1 997
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish)
- Version / remarks:
- 1981
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- Body responsible for the test
- IUPAC Name:
- Body responsible for the test
- Test material form:
- not specified
Constituent 1
- Radiolabelling:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Cyprinus carpio
Study design
- Route of exposure:
- aqueous
- Test type:
- flow-through
- Water / sediment media type:
- natural water: freshwater
- Total exposure / uptake duration:
- 4 d
Test conditions
- Test temperature:
- Test (solution) temperature: 24.9 °C (min.) ... 251.3 °C (max.)
- Details on test conditions:
- Duration of test: 56 d;
no. of samples: 56 - Nominal and measured concentrations:
- Concentration of test material used: 0.5 mg/L
- Reference substance (positive control):
- not specified
- Details on estimation of bioconcentration:
- Method of calculation: Steady state
Results and discussion
Bioaccumulation factor
- Type:
- BCF
- Value:
- <= 27 dimensionless
- Basis:
- not specified
- Calculation basis:
- steady state
- Remarks on result:
- other: Conc.in environment / dose:0.5 mg/L
- Details on results:
- The bioconcentration factors of the test substance are less than 27 and the compound is not accumulative in fish.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- BCF ≤ 27, not accumulative in fish
- Executive summary:
The degree of bioconcentration in fish (Cyprinus carpio) of the test substance has been determined in a GLP study according to OECD Guideline 305C. The bioconcentration factors are less than 27 and hence, the compound is not accumulative in fish.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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