Registration Dossier

Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study obtained through inquiry process; SNIF file obtained from ECHA.

Data source

Reference
Reference Type:
other: SNIF
Title:
Unnamed
Year:
1997

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish)
Version / remarks:
1981
Deviations:
not specified
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
not specified
Radiolabelling:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Cyprinus carpio

Study design

Route of exposure:
aqueous
Test type:
flow-through
Water / sediment media type:
natural water: freshwater
Total exposure / uptake duration:
4 d

Test conditions

Test temperature:
Test (solution) temperature: 24.9 °C (min.) ... 251.3 °C (max.)
Details on test conditions:
Duration of test: 56 d;
no. of samples: 56
Nominal and measured concentrations:
Concentration of test material used: 0.5 mg/L
Reference substance (positive control):
not specified
Details on estimation of bioconcentration:
Method of calculation: Steady state

Results and discussion

Bioaccumulation factor
Type:
BCF
Value:
<= 27 dimensionless
Basis:
not specified
Calculation basis:
steady state
Remarks on result:
other: Conc.in environment / dose:0.5 mg/L
Details on results:
The bioconcentration factors of the test substance are less than 27 and the compound is not accumulative in fish.

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
BCF ≤ 27, not accumulative in fish
Executive summary:

The degree of bioconcentration in fish (Cyprinus carpio) of the test substance has been determined in a GLP study according to OECD Guideline 305C. The bioconcentration factors are less than 27 and hence, the compound is not accumulative in fish.