Registration Dossier
Registration Dossier
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EC number: 422-600-5 | CAS number: 73936-91-1
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study obtained through inquiry process; SNIF file obtained from ECHA.
Data source
Reference
- Reference Type:
- other: SNIF
- Title:
- Unnamed
- Year:
- 1 997
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish)
- Version / remarks:
- 1981
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- Body responsible for the test
- IUPAC Name:
- Body responsible for the test
- Test material form:
- not specified
Constituent 1
- Radiolabelling:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Cyprinus carpio
Study design
- Route of exposure:
- aqueous
- Test type:
- flow-through
- Water / sediment media type:
- natural water: freshwater
- Total exposure / uptake duration:
- 4 d
Test conditions
- Test temperature:
- Test (solution) temperature: 24.9 °C (min.) ... 251.3 °C (max.)
- Details on test conditions:
- Duration of test: 56 d;
no. of samples: 56 - Nominal and measured concentrations:
- Concentration of test material used: 0.5 mg/L
- Reference substance (positive control):
- not specified
- Details on estimation of bioconcentration:
- Method of calculation: Steady state
Results and discussion
Bioaccumulation factor
- Type:
- BCF
- Value:
- <= 27 dimensionless
- Basis:
- not specified
- Calculation basis:
- steady state
- Remarks on result:
- other: Conc.in environment / dose:0.5 mg/L
- Details on results:
- The bioconcentration factors of the test substance are less than 27 and the compound is not accumulative in fish.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- BCF ≤ 27, not accumulative in fish
- Executive summary:
The degree of bioconcentration in fish (Cyprinus carpio) of the test substance has been determined in a GLP study according to OECD Guideline 305C. The bioconcentration factors are less than 27 and hence, the compound is not accumulative in fish.
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