Registration Dossier
Registration Dossier
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EC number: 203-354-6 | CAS number: 106-02-5
Endpoint summary
Administrative data
Description of key information
Additional information
No experimental BCF studies (aquatic and terrestrial) are available.
An in silico method for calculating BCF has been employed. Based on the BCF/BAF method of Arnot-Gobas and including biotransformation rate, a BCF value between 500 and 1000 is obtained regardless of the trophic level.
The substance is not acutely toxic (no toxicity found at the limit of solubility) and is very poorly soluble in water. Chronic studies have been performed on the substance and read-across substance (EC 422-320-3), and the chronic NOECs for algae, daphnids and fish are known. Nevertheless, it would be technically challenging to perform a BCF study on fish at concentrations below the NOEC (of 0.027 mg/L) as apart from the low water solubility, the substance also has a high adsorption coefficient and readily biodegrades. Due to the ready degradation, rapid metabolism is also assumed and a BCF study performed on this substance would not be expected to add significantly to the knowledge already gained.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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