Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 245-659-7 | CAS number: 23432-62-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Not readily biodegradable: 15.5 - 19.5% after 28 d (O2 consumption, EU C.4-D)
Key value for chemical safety assessment
Additional information
Experimental data were not available for methyl-N- [3-(trimethoxysilyl)propyl]carbamate (CAS 23432-62-4), therefore read across from the comparable substance, methyl-N-{[dimethoxy(methyl)silyl]methyl}carbamate (CAS 23432-65-7) was deemed acceptable for assessment.
Both methyl-N- [3-(trimethoxysilyl)propyl]carbamate (CAS 23432-62-4) and methyl-N-{[dimethoxy(methyl)silyl]methyl}carbamate (CAS 23432-65-7) are within an analogue group of substances within which, in general, there is no evidence of any significant biodegradation. Substances within this wider analogue group, in general, exhibit no evidence of any significant biodegradation once hydrolysis and subsequent biodegradation of alkoxy/acetoxy groups has been taken into account.
It is therefore considered valid to read-across the results for methyl-N {[dimethoxy(methyl)silyl]methyl}carbamate (CAS 23432-65-7) to fill the data gap for the registered substance. This wider analogue group for the ready biodegradability endpoint consists of a number of sub-classes of substances. However, read-across is carried out between substances with the same sub-class in most cases.
The table below presents ready biodegradation data available for substances within the sub-class of the III-10 structural class: carbamates.
Ready biodegradation data available for substances within the relevant sub-class of chemicals
CAS |
Name |
Readily biodegradable? Yes/No |
Result: Biodegradation after 28 days |
Guideline |
Reliability |
Corrected % biodegradation once alkoxy/acetoxy biodegradation is accounted for |
023432-65-7 |
Methyl-N-{[dimethoxy(methyl)silyl]methyl}carbamate |
No |
19-20% |
OECD 301F |
1a |
-13 |
023432-64-6 |
Carbamic acid, [(trimethoxysilyl)methyl]-, methyl ester |
No |
42% |
OECD 301F |
1a |
-8 |
The study with methyl-N-{[dimethoxy(methyl)silyl]methyl}carbamate (CAS 23432-65-7) was performed according to EU C.4-D (GLP; Hertl, 2002). Since the substance is expected to hydrolyse rapidly in contact with water (DT50: 1.9 h at 20 - 25 °C, pH 7), the result from this study mainly reflects the biotic degradation of the hydrolysis products. The hydrolysis products are methyl-N-{[dihydroxy(methyl)silyl]methyl}carbamate und methanol. After 28 d a degradation of 15.5 - 19.5% (O2 consumption) was recorded. Methanol is known to be readily biodegradable (OECD, 2004). Thus, the final result is mainly attributed to the second hydrolysis product methyl-N-{[dihydroxy(methyl)silyl]methyl}carbamate which is considered not to be readily biodegradable according to the OECD criteria. The study is considered to be reliability 1 (reliable without restrictions); the read across of the result is considered to be reliability 2 (reliable with restrictions).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
