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Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Qualifier:
equivalent or similar to
Guideline:
other: other guideline: Screening test is similar to the preliminary test in OECD guideline for the testing of chemicals, No. 105, Water Solubility
Principles of method if other than guideline:
The solubility of the test substance is investigated in a combined screening test (which is similar to OECD TG 105) followed by LCMS analysis of solutions obtained in the screening test.
GLP compliance:
not specified
Key result
Medium:
n-octanol
Solubility:
340 g/L
Temp.:
23 °C
Remarks on result:
other: analysed using LCMS
Conclusions:
Under the test conditions, the octanol solubility of the test substance was determined to be 340 g/L in 1-octanol at 23°C.
Executive summary:

The octanol solubility for the test substance tallow alkyl trimethyl ammonium chloride was determined with a combined screening test and LCMS analysis. The measurement was performed at room temperature, approximately 23°C. Under the test conditions, the octanol solubility of the test substance was determined to be 340 g/L in 1-octanol at 23°C.

Description of key information

 The solubility in organic solvents was determined according to a method that is similar to OECD Guideline 105 (combined screening test and LCMS analysis) (Farnback, 2012).

Key value for chemical safety assessment

Solubility in organic solvents at 20°C:
340 g/L

Additional information

at 23 °C