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EC number: 292-429-7
CAS number: 90622-29-0
CAL 145 comprises alkenes C13-14 hydroformylation products with
read-across from the chemically-similar Alchisor CAL 123 as defined in
the `Read-Across Justification Document'. Where
toxicological data exist for Alchisor CAL 123, these are representative
of the Alchisor CAL 145 substance.
substance is a complex UVCB which contains a variety of esters,
alcohols, ethers and paraffins.
components and functional groups within these substances could undergo a
variety of Phase I metabolism reactions, for example oxidation of
alcohol groups to aldehydes and/or carboxylic acids, followed by Phase
II conjugation reactions. The ester components might also undergo some
degree of hydrolysis to the corresponding carboxylic acid and alcohol
Molecular Weight of the component substances would indicate that some
degree of absorption is possible. Furthermore any hydrolysis of the
ester components will create lower MW species which would be more easily
substance is relatively poorly soluble in water (<1.2 mg/l). The Log Pow
is 6. The high lipophilicity will tend to limit absorption.
substance did not give rise to any signs of toxicity in any of the
available toxicology studies at doses of up to 2000 mg/kg and hence
provides no direct evidence regarding its toxicokinetic behaviour.
the available structural data, phys-chem properties and toxicology
data, it is likely that the substance is very poorly absorbed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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