Registration Dossier

Ecotoxicological information

Toxicity to birds

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Link to relevant study record(s)

Description of key information

Alchisor CAL 145 comprises alkenes C13-14 hydroformylation products with read-across from the chemically-similar Alchisor CAL 123 as defined in the `Read-Across Justification Document'.  Where environmental toxicity data exist for Alchisor CAL 123, these are representative of the Alchisor CAL 145 substance.  In accordance with REACH Annex X, the requirement for an avian toxicity study is waived on the basis of ready biodegradability and the absence of toxicity to mammals. The substance is considered to be unlikely to accumulate through the food chain. No reliable measured bioconcentration information is available for Alchisor CAL 145.

Key value for chemical safety assessment

Additional information

Using read-across, Alchisor CAL 123 is not considered to be toxic to mammals based on the evidence presented in this dossier. Acute oral and acute dermal toxicities in rat were > 2000 and >2020 mg/kg, respectively based on the study by Kuhn (2010). Using this evidence it is assumed that Alchisor CAL 145 is not considered to be toxic (in PBT terms) to mammals. It is reasonable to assume that toxicity will not be seen in birds and that secondary poisoning is unlikely to occur in the environment, therefore the requirement for a PNECoral is waived.