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EC number: 700-071-4
CAS number: 932742-30-8
dermal toxicity study (Limit Test), according to OECD 402 Guideline and
EU Method B. was performed with SIKA Hardener LI in rats. Five male and
five female Wistar rats were treated with SIKA Hardener LI by single
administration at a dose level of 2000 mg/kg bw of SIKA Hardener LI in
its original form for 24-hour in a semi-occlusive manner. No mortalities
occurred , neither in male nor in female rats during the 14 days
observation period. Behaviour and general state of animals were
considered to be normal. All pathological findings were considered
incidental changes with no indication of test item related effects.
Thus, under the conditions of this study, single 24-hour dermal
administration of the test item SIKA Hardener LI did not induce any test
item related adverse effects.
dermal LD0 and LD50 values of SIKA Hardener LI were 2000 mg/kg bw and
greater than 2000 mg/kg bw , respectively, in male and in female Wistar
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