Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 945-888-9
CAS number: -
In a primary eye irritation study
conducted according to OECD guideline 492, 50 mg of Ytterbium
stabilized Zirconium and Hafnium Oxide (Purity >99.5%) was
applied topically on EpiOcular tissue, a reconstituted three-dimensional
human corneal epithelium modelfor 6 h and a post-treatment period of 18
h compared to that of the concurrent negative control. Irritation was
scored by the method of mean relative tissue viability.
The mean relative tissue viability
(% negative control) was > 60% (60.2%). As the results were within the
borderline values (60 ± 5%), a second experiment was performed to
confirm the first results. The mean relative tissue viability
(% negative control) of the second experiment was > 60% (99.2%) and the
test item did not show irritant effects. Based on these results, the
test item can be classified as a non-irritant according to the UN GHS
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Questo sito web si avvale di cookie affinché possiate usufruire della migliore esperienza sui nostri siti web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again