Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 945-888-9
CAS number: -
- The mean absolute OD570of
the three negative control tissues was ≥0.8
and ≤ 2.8 (1.907)
- The mean relative tissue viability
(% negative control) of the positive control was ≤
- Standard deviation of viability of
replicate tissues of all dose groups was ≤ 18% (0.2% - 5.3%)
Table 1: Mean Relative Tissue Viability for
the test item
Mean Relative Tissue Viability [%]
In a primary skin irritation study conducted
according to the guideline OECD 439, 25 mg of zirconium
oxide, hafnium and ytterbium doped (purity > 95 %) was topically applied
to the EpiDerm
for 60 min followed by a 42 h post-incubation period. Irritant
potential of the test item was predicted from the relative mean tissue
viabilities obtained compared to the corresponding negative control
tissues concurrently treated with DPBS. The
controls confirmed the validity of the study. The
mean relative tissue viability (% negative control) was observed to be
> 50% (92.8%). Based on these results, the test item is classified as a
non-irritant under the UN GHS Criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Questo sito web si avvale di cookie affinché possiate usufruire della migliore esperienza sui nostri siti web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again