Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Additional information

Animal data suggest a total absence of toxicity by oral and dermal routes. Data from the inhalative route are not reliable.

However, there are reports of effects in workers including dizziness, headaches. Organic nitrates have vasodilatation properties that could account for such effects. There is also a problem of habituation to their effects, followed by possible effects upon cessation of exposure.

Justification for classification or non-classification

As a worst-case, Xn, R20/21/22 and Acute tox 4 are proposed based on human data (corresponding dose-levels unknown).