Registration Dossier

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25 March 1998 to 09 October 1998
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: compliant to GLP and testing guideline; adequate coherence between data, comments and conclusions
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
yes
Remarks:
Presaturation time at 30 °C was limited to 30, 60 and 90 minutes as described in the method supplied by the sponsor instead of 24, 48 and 72 hours. The pH of the test solution was not measured.
GLP compliance:
yes (incl. certificate)
Type of method:
flask method
Water solubility:
12.5 mg/L
Temp.:
20 °C
Remarks on result:
other: The pH of the test solution was not measured (the test substance was assumed to have no influence on the pH of the solution)
Details on results:
The average solubility from the 6 flasks is 12.53 mg/l, the confidence interval at 95 % confidence level is calculated as ± 1.18 mg/l.
Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The solubility of NEH in water at 20 °C was found to be 12.5 ± 1.2 mg/l

Description of key information

Key value for chemical safety assessment

Water solubility:
12.5 mg/L
at the temperature of:
20 °C

Additional information