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EC number: 607-759-2
CAS number: 25618-55-7
Growth: was monitored from weaning to mating
during the first 4 months of each generation. The weights of the females
were recorded at weaning and mating while the weight of the males was
recorded at weaning and at day 65. There were no significant differences
between weights in treated or control rats.
Food intake: was not recorded in this study,
but a previous study indicates that levels of 5% PGPR in the diet had no
effects on food intake.
Survival and clinical signs: the rats were
observed daily. There were no deaths and no evidence of abnormal
behaviour or functional disorders in all 3 generations.
in general for both grups the breeding
performance was better in the 1st and 3rd generation. In the 2nd
generation the breeding was poor in the control and PGPR group. The only
significant difference was a greater percentage in the controls of
litters weaned entirely which was reversed in favour of the PGPR rats in
the third generation. Besides, the 2nd generation had a larger
proportion of males among the weaned rats fed PGPR.
In the generation 1 and 3 a high percentage
of the offspring were weaned for both groups. In the 2nd generation were
was a reduction
in both groups in the percentage of the
animals weaned. Since this reduction occurred in both groups and to
similar extend, it was caused by an unknown environmental factor.
examination of selected tissues from those rats continued for 1 year
failed to show any lesions which could be ascribed to the consumption of
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