Registration Dossier
Registration Dossier
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EC number: 944-572-8 | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
LC50 (96h) = 1.1 mg/L (nominal) for Danio rerio (EU method C.1, read across)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 1.1 mg/L
Additional information
Since no studies assessing the short-term toxicity of 5-[C11-12 (branched) alkyl]-2-hydroxybenzaldehyde oxime to fish is available, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 Grouping of substances, a read-across to the structurally related source substance Benzaldehyde, 2-hydroxy-5-nonyl, oxime, branched (CAS 174333-80-3) was conducted. The analogue justification document is attached to chapter 13.
The study with the read across substance was performed according to GLP and EU method C.1 using Danio rerio as test organism (Scholz 1996). The test material was applied directly to the test vessels. Analytical monitoring in water was omited due to the very low water solubility. All validity criteria were fulfilled. The LC50 is determined to be 1.1 mg/L based on nominal concentration. Based on the high structural similarity which leads to similar behavior in the environment (see analogue justification document) this conclusion can also be considered true for 5-[C11-12 (branched) alkyl]-2-hydroxybenzaldehyde oxime.
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