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EC number: 500-281-4
CAS number: 98362-33-5
no further remarks
It was the aim of this study to reveal acute toxic effects of
2,3-Epoxypropyl neodecanoate, oligomeric reaction products with
after a single administration per inhalation as a liquid aerosol.
was administered as aerosol with a mass median aerodynamic diameter of
2.0µm per inhalation to Sprague Dawley rats. The test substance was
applied for 4 hours in a nose-only inhalation device. The actual
concentration of the aerosol was1.9mg per litre air which is under the
limit concentration for this kind of tests. Five male and fivefemale
animals were exposed. The inhalation exposure of rats to
at the maximal technically feasible concentration of 1.9 mg/L did not
produce signs of toxicity. All animals survived and no adverse effects
were observed during the 14-day observation period.
The LC50, per inhalation, four hours exposure, of
for male and female rats is therefore greater than 1.9 mg/L air which is
the highest technically feasible aerosol concentration.
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