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EC number: 500-281-4
CAS number: 98362-33-5
The NOAEC (inhalatory; rep. dose) was converted to a corrected NOAEC for
the correction of the inhalation absorption in rats to the inhalation
absorption in humans.
For the correction the following calculation was applied: 202 mg/m3 x
0,75 x 0,67 = 101 mg/m3
(according to eCHA Guidance, Chapter R8, Figure R. 8). The corrected
NOAEC is 101 mg/m3.
The NOAEC (inhalatory; rep. dose) was converted to a correction of the
inhalation absorption in rats to the inhalation absorption in humans.
(according to ECHA Guidance, Chapter R8, Figure R.8). The corrected
NOAEC is 101 mg/m3.
2,3-Epoxypropyl neodecanoate, oligomeric reaction products with
toluene-4-sulfonic acid is exclusively used in chemical processes (i.e.
a catalysator for industrial and professional use). A direct use of this
substance is not known. The exposure of consumers to the substance is
unlikely to occur via consumer products, because no consumer product is
known to contain the substance. An exposure of consumers or general
population via the environment is also unlikely to occur, because there
are only low levels of exposure from environmental sources, and the
substance released to the environment would rapidly be degraded by water
and photooxidants. Therefore, DNELs for consumers or general population
are not applicable as consumers are not involved in the industrial or
professional use of 2,3-Epoxypropyl neodecanoate, oligomeric reaction
products with toluene-4-sulfonic acid or of preparations containing this
An indirect exposure of the general
population via the environment might occur through ingestion of
foodstuff or drinking water. Therefore, a systemic oral long-term DNEL
for general population is derived and will be used to assess any
possible risk that could result from indirect exposure of man via the
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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