(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol

Bioaccumulation: aquatic / sediment

Description of key information

The BCFs of the test substance ranged from less than 2.0 to 14 at Level 1 (test concentration 0.3 mg/L) and less than 15 to 37 at Level 2 (test concentration 0.03 mg/L).

Key value for chemical safety assessment

BCF (aquatic species):

37 dimensionless

Additional information

Bioaccumulation test of 3,4 -DMBS in common carp

Test conditions:

Acute toxicity test:

(1) Test fish: Ricefish (Oryzia latipes)

(2) Duration of exposure: 48 hours

(3) Exposure method: Semi-static system (Renewal of test water at every 8 - 16 hours)

Bioaccumulation test:

(1) Test fish: Common carp (Cyprinus carpio)

(2) Nominal concentrations of test substance:

High exposure level (Level 1): 0.3 mg/L

Low exposure level (Level 2): 0.03 mg/L

(3) Duration of exposure: 8 weeks

(4) Exposure method: Flow-through system

(5) Analytical method: High performance liquid chromatography

Results:

(1) 48 -hour LC50 value:≥100 mg/L

(2) Biocentration factors:

Level 1: 2.0 - 14

Level 2: 15 - 37

Stability:

The test substance was stable under storage and test conditions.