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EC number: 413-110-2
CAS number: 135861-56-2
A study was performed to assess the actue dermal toxicity of the test
material in the Sprague-Dawley CD strain rat. The method used followed
that described in the OECD Guidelines for Testing of Chemicals No. 402
"Acute Dermal Toxicity" and Method B3 of Commission Directive 92/69/EEC.
A group of 10 animals (5 males and 5 females) was given a single
24-hour, semi-occluded dermal application to intact skin at a dose level
of 2000 mg/kg bodyweight. The animals were observed for 14 days after
the day of treatment and were then killed for gross pathological
There were no deaths. No signs of systemic toxicity or skin irritation
were noted during the study.
All animals showed an expected gain in bodyweight during the study.
No abnormalities were noted at necropsy.
The acute dermal median lethal dose (LD50) of the test
material in the Sprague-Dawley CD strain rat was found to be > 2000
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