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EC number: 244-168-5
CAS number: 21041-95-2
A study was conducted to determine the effects of sub-chronic exposure in lungs and reproductive system of B6C3F1 mice.
Groups of mice were exposed to the test material at 0, 0.025, 0.05, 0.1, 0.25 or 1 mg/m3 for 6 h/d, 5 d/wk for 13 wk. Animals were observed twice daily for mortality and signs of toxicity and were weighted on day 1, weekly thereafter and on the day of necropsy. Clinical observations were recorded daily. Following organs were weighed at necropsy: heart, right kidney, liver, lungs, spleen, right testis and thymus.
Available data shows treatment-related respiratory tract lesions in the lungs, nose and larynx of B6C3F1 mice exposed by inhalation to CdO for 13 wk. However, reproductive toxicity was not observed at any exposure level.
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