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EC number: 244-168-5
CAS number: 21041-95-2
- appearance, behaviour, food consumption, growth and mortality of
treated rats of all groups were not affected
- no increased blood
- no change in
- not found liver
- no effect on renal
- pituitary, adrenals,
thyroid, heart, brain, gonads, urinary bladder, uterus, spleen, stomach,
intestines and thymus were unaffected
- no effect or only a
small effect (10–20% decrease) on body weight
- no testicular
- no decrease in male
- no adverse
Cadmium (in the form of CdCl2) was fed to groups of 20
male and 20 female rats each over a period of 3 months in
concentrations of 0, 1, 3, 10 and 30 ppm. Appearance,
behaviour, food consumption, growth and mortality of the
treated rats of all groups were not affected during the
3-month period. The cadmium concentrations did not cause
blood, liver or kidney damage. The systolic blood pressure
of the treated animals was not increased. Autopsies and
histopathological investigation of the animals showed no
sign of any alterations. Cadmium accumulated
dose-dependently in the kidneys and liver. Concentrations
of cadmium up to 30 ppm in their feed were tolerated by
rats over a period of 3 months without harm.
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