Registration Dossier

Physical & Chemical properties

Endpoint summary

Administrative data

Description of key information

Appearance:

On the basis of physical observation and using the sense of smell, 2-Naphthalenesulfonic acid, 7-amino-4-hydroxy-3-[[2-methoxy-5-methyl-4-[[2-(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8-[[2-sulfo-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt was observe to be a solid red powder.

Melting point:

The melting point determination of tetrasodium 7 -amino-4 -hydroxy-3 -[(E)-2 -{2 -methoxy-5 - methyl-4 -[2 -(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]-8 -[(E)-2 -{2 -sulfonato-4 -[2 - (sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]naphthalene-2 -sulfonate (CAS No. 503155 -49 -5) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and man decomposition temp was determine to be 161.3°C at 964.3 hPa.

Boiling Point:

The study does not need to be conducted because the substance is a solid which decomposes before boiling. The melting point determination of Test item tetrasodium 7 -amino-4 -hydroxy-3 -[(E)-2 -{2 -methoxy-5 -methyl-4 -[2 -(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]-8 -[(E)-2 -{2 -sulfonato-4 -[2 -(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]naphthalene-2 -sulfonate (CAS No. 503155 -49 -5 ) was done as per the test guideline OECD 102. The method followed was according to Capillary/metal block. The man decomposition temp was determine to be 161.3°C at 964.3 hPa.

Density:

The density of Test item tetrasodium 7 -amino-4 -hydroxy-3 -[(E)-2 -{2 -methoxy-5 -methyl-4 -[2 -(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]-8 -[(E)-2 -{2 -sulfonato-4 -[2 -(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]naphthalene-2 -sulfonate (CAS No.503155-49-5 ) was determined following OECD guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition, 2014. The pour density and tapped density of the test item was determine to be 0.4882 g/cm³ and 0.7419 g/cm³ at 25°C and 964.65 hPa.

Particle size distribution:

The particle size distribution of test item tetrasodium 7 -amino-4 -hydroxy-3 -[(E)-2 -{2 -methoxy-5 -methyl-4 -[2 -

(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]-8 -[(E)-2 -{2 -sulfonato-4 -[2 - (sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]naphthalene-2 -sulfonate (CAS No. 503155-49-5 ) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determine to be in the range of 150 micron to 106 micron.

Vapour pressure:

The estimated vapour pressure of 2 -Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt at 25 deg C was 9.05E-43 kPa.

Partition coefficient:

Based on the available data from modeling database EPI suite using the KOWWIN V1.68 programme, the estimated logPOW of the chemical 2-Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt was estimated to be -3.5. On the basis of this estimated value, substance 2 -Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt can be considered to be hydrophilic in nature.

Water solubility:

The water solubility determination of test substance  tetrasodium 7 -amino-4 -hydroxy-3 -[(E)-2 -{2 -methoxy-5 -methyl-4 -[2 -

(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]-8 -[(E)-2 -{2 -sulfonato-4 -[2 - (sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]naphthalene-2 -sulfonate (CAS No. 503155 -49 -5 ) was done as per the spectrophotometric analytical method is 184.620 g/L at 25 Deg C.

From this solubility value it is concluded that chemical is very soluble in water.

Surface tension:

Based on the data from ACD labs, surface tension for 2 -Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt (CAS no. 503155 -49 -5) was predicted to be 88.5 mN/m.

Flash point:

The flash point determination of Test item tetrasodium 7 -amino-4 -hydroxy-3 -[(E)-2 -{2 -methoxy-5 -methyl-4 -[2 - (sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]-8 -[(E)-2 -{2 -sulfonato-4 -[2 - (sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]naphthalene-2 -sulfonate (CAS No. 503155 -49 -5 )was done. The method was closed cup method using Pensky-Martens Flash Point Apparatus. The mean flash point of the test item was determine to be 185°C at 964.6 hPa.

Auto flammability:

2-Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy) ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt (CAS no. 503155 -49 -5) did not catch fire on being exposed to air at room temperature of 27°C pressure of 966 hPa. This indicates that 2 -Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 - [[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt (CAS no. 503155 -49 -5) is not auto-flammable.

Flammability:

2 -Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 2 -Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 2 -Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt was considered non-flammable.

Explosiveness:

The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.

Oxidizing properties:

The study does not need to be conducted because the substance is a solid.

pH:

The pH determination of test item tetrasodium 7 -amino-4 -hydroxy-3 -[(E)-2 -{2 -methoxy-5 -methyl-4 -[2 - (sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]-8 -[(E)-2 -{2 -sulfonato-4 -[2 - (sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]naphthalene-2 -sulfonate (CAS No. 503155 -49 -5 ) was done as per the test guideline OECD 122. The mean pH of the test solutionwas determined with the help of digital pH meter. The mean pH was determine to be 4.40 at 26.3 °C.

Additional information

Appearance:

On the basis of physical observation and using the sense of smell, 2-Naphthalenesulfonic acid, 7-amino-4-hydroxy-3-[[2-methoxy-5-methyl-4-[[2-(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8-[[2-sulfo-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt was observe to be a solid red powder.

Melting point:

The melting point determination of tetrasodium 7 -amino-4 -hydroxy-3 -[(E)-2 -{2 -methoxy-5 - methyl-4 -[2 -(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]-8 -[(E)-2 -{2 -sulfonato-4 -[2 - (sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]naphthalene-2 -sulfonate (CAS No. 503155 -49 -5) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and man decomposition temp was determine to be 161.3°C at 964.3 hPa.

Boiling Point:

The study does not need to be conducted because the substance is a solid which decomposes before boiling. The melting point determination of Test item tetrasodium 7 -amino-4 -hydroxy-3 -[(E)-2 -{2 -methoxy-5 -methyl-4 -[2 -(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]-8 -[(E)-2 -{2 -sulfonato-4 -[2 -(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]naphthalene-2 -sulfonate (CAS No. 503155 -49 -5 ) was done as per the test guideline OECD 102. The method followed was according to Capillary/metal block. The man decomposition temp was determine to be 161.3°C at 964.3 hPa.

Density:

The density of Test item tetrasodium 7 -amino-4 -hydroxy-3 -[(E)-2 -{2 -methoxy-5 -methyl-4 -[2 -(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]-8 -[(E)-2 -{2 -sulfonato-4 -[2 -(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]naphthalene-2 -sulfonate (CAS No.503155-49-5 ) was determined following OECD guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition, 2014. The pour density and tapped density of the test item was determine to be 0.4882 g/cm³ and 0.7419 g/cm³ at 25°C and 964.65 hPa.

Particle size distribution:

The particle size distribution of test item tetrasodium 7 -amino-4 -hydroxy-3 -[(E)-2 -{2 -methoxy-5 -methyl-4 -[2 -

(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]-8 -[(E)-2 -{2 -sulfonato-4 -[2 - (sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]naphthalene-2 -sulfonate (CAS No. 503155-49-5 ) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determine to be in the range of 150 micron to 106 micron.

Vapour pressure:

Modified Grain method was used to estimate the vapour pressure of 2 -Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt (CAS no. 503155 -49 -5) using MPBPVP v1.43 of EPI SUITE.

The estimated vapour pressure of 2 -Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt (CAS no. 503155 -49 -5) at 25 deg C was 9.05E-43 kPa.

Partition coefficient:

Based on the available data from modeling database EPI suite using the KOWWIN V1.68 programme, the estimated logPOW of the chemical 2-Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt was estimated to be -3.5. On the basis of this estimated value, substance 2 -Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt can be considered to be hydrophilic in nature.

Water solubility:

The water solubility determination of test substance  tetrasodium 7 -amino-4 -hydroxy-3 -[(E)-2 -{2 -methoxy-5 -methyl-4 -[2 -

(sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]-8 -[(E)-2 -{2 -sulfonato-4 -[2 - (sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]naphthalene-2 -sulfonate (CAS No. 503155 -49 -5 ) was done as per the spectrophotometric analytical method is 184.620 g/L at 25 Deg C.

From this solubility value it is concluded that chemical is very soluble in water.

Surface tension:

Based on the data from ACD labs, surface tension for 2 -Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt (CAS no. 503155 -49 -5) was predicted to be 88.5 mN/m.

Flash point:

The flash point determination of Test item tetrasodium 7 -amino-4 -hydroxy-3 -[(E)-2 -{2 -methoxy-5 -methyl-4 -[2 - (sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]-8 -[(E)-2 -{2 -sulfonato-4 -[2 - (sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]naphthalene-2 -sulfonate (CAS No. 503155 -49 -5 )was done. The method was closed cup method using Pensky-Martens Flash Point Apparatus. The mean flash point of the test item was determine to be 185°C at 964.6 hPa.

Auto flammability:

2-Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy) ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt (CAS no. 503155 -49 -5) did not catch fire on being exposed to air at room temperature of 27°C pressure of 966 hPa. This indicates that 2 -Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 - [[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt (CAS no. 503155 -49 -5) is not auto-flammable.

Flammability:

2 -Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 2 -Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 2 -Naphthalenesulfonic acid, 7 -amino-4 -hydroxy-3 -[[2 -methoxy-5 -methyl-4 -[[2 -(sulfooxy)ethyl]sulfonyl] phenyl]azo]-8 -[[2 -sulfo-4 -[[2 -(sulfooxy)ethyl]sulfonyl]phenyl]azo]-, tetrasodium salt was considered non-flammable.

Explosiveness:

The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.

Oxidizing properties:

The study does not need to be conducted because the substance is a solid.

pH:

The pH determination of test item tetrasodium 7 -amino-4 -hydroxy-3 -[(E)-2 -{2 -methoxy-5 -methyl-4 -[2 - (sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]-8 -[(E)-2 -{2 -sulfonato-4 -[2 - (sulfonatooxy)ethanesulfonyl]phenyl}diazen-1 -yl]naphthalene-2 -sulfonate (CAS No. 503155 -49 -5 ) was done as per the test guideline OECD 122. The mean pH of the test solutionwas determined with the help of digital pH meter. The mean pH was determine to be 4.40 at 26.3 °C.