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EC number: 230-528-9 | CAS number: 7173-62-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
Three long-term sediment tests are performed with a diamine with a hydrogenated tallow alkyl chain.
It is considered to be justified to use these results also for other C10-18 diamines because in contrast to the difference in toxicity observed for the aquatic compartment only a limited difference is expected for the benthic compartment because the main exposure route for both the nematode and lumbriculus will be through uptake via food (comber et al., 2008) and because only a small difference in sorption to sediment for the diamines with different alkyl chains is anticipated.
Key value for chemical safety assessment
- EC10, LC10 or NOEC for freshwater sediment:
- 86 mg/kg sediment dw
Additional information
For diamines, four test results are available regarding the sediment toxicity. Three long-term studies and one short-term study. The long term studies were performed with the hydrogenated diamine C16 -18 and were performed withLumbriculus variegatus and Caenorhabditis elegans. The long-term study with Caenorhabditis elegans showed no effects upto 1000 mg/kg dw. Two long-term tests withLumbriculus variegatus were performed applying two different spiking approaches. In the first test a solvent was used to spike the test substance on the sand fraction and in the second test the test substance was spiked onto the whole sediment in the water phase at a slightly elevated temperature. In the first test with solvent spiking, a significant difference in reproduction between the normal control and solvent control was observed. It was not clear why this difference was observed but considering to unrealism in using a solvent to spike the test substance it was decided to repeat the test using an environmentally more realistic solvent free spiking procedure of the whole sediment. For this second long-termLumbriculus variegatus a NOEC and EC10 for reproduction was observed of resp. 180 mg/kg dw and 86 mg/kg dw. The NOEC and EC10 based on dry weight of resp 360 and 237 mg/kg dw are higher probably because the moment of splitting of the worms is slightly influenced by the test substance.
The spiking procedure using a solvent to spike the sand fraction is unrealistic for cationic surfactants. Cationic surfactants which may enter surface water are normally sorbed to dissolved organic matter or suspended matter and may redistribute slowly to thermodynamically more favourable sites when available. Quartz sand has a very low CEC and no organic matter. The use of natural sediment spiked without using solvent is far more realistic and could allow a more evenly distribution of the test substance over the sediment. In addition it would allow the ingestion of the test substance more realistically. In addition the solvent apparently had a positive influence on the reproduction which limits the reliability of the result.
A
similar toxicity is anticipated for organisms living in the benthic
compartments for diamines with alkyl chain lengths ranging from C10-18
based on the fact that the main exposure route for sorbing substances is
via ingestion (comber 2008) and limited difference in sorption to
sediment because the main driver in alkyl-1,3 -diaminopropanes sorption is
ionic interaction. Read-across of these sediment results to diamines with
other alkyl-chain lengths is considered to be justified.
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