Registration Dossier

Administrative data

Endpoint:
short-term toxicity to birds: acute oral toxicity test
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Well documented publication

Data source

Reference
Reference Type:
publication
Title:
The acute oral toxicity, repellency, and hazard potential of 998 chemicals to one or more species of wild and domestic birds
Author:
Schafer EW, Bowles WA and Hurlbut J
Year:
1983
Bibliographic source:
Arch. Environ. Contam. Toxicol. 12, 355-382 (1983)

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Wild trapped birds were preconditioned to captivity for 2 to 6 weeks and were usually dosed by gavage with solutions or suspensions of the test substance in propylene glycol. Other oral dosing methods were occiasionally used.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid
Dose method:
gavage
Analytical monitoring:
no
Vehicle:
yes
Details on preparation and analysis of diet:
Name of vehicle: Propylene glycol

Test organisms

Test organisms (species):
other: Agelaius phoeniceus, Coturnix coturnix
Details on test organisms:
- Source: Wild trapped specimen
- Acclimatisation: 2 to 6 weeks in captivity

Results and discussion

Effect levelsopen allclose all
Key result
Dose descriptor:
LD50
Effect level:
> 100 other: mg/kg
Conc. / dose based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: Species: Agelaius phoeniceus
Key result
Dose descriptor:
LD50
Effect level:
> 1 000 other: mg/kg
Conc. / dose based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: Species: Coturnix coturnix

Applicant's summary and conclusion