Registration Dossier

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

-1.16 at 25 °C

Key value for chemical safety assessment

Log Kow (Log Pow):
-1.16
at the temperature of:
25 °C

Additional information

The partition coefficient of the test substance was determined by the shake flask method according to OECD guideline 107 (BASF, BRU 88.137, 1988). A log Pow value of -1.16 at 25 °C was observed. This result is supported by a calculation using EpiSuite v4.11 (BASF, 2017). The log Kow calculated by KOWWIN program v1.68 is -0.74.

QSAR-disclaimer
In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met. Furthermore according to Article 25 of the same Regulation testing on vertebrate animals shall be undertaken only as a last resort.
According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.
For the assessment of 2-imidazolidone (Q)SAR results were used for partition coefficient. The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.
Therefore, further experimental studies on partition coefficient are not provided.