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EC number: 267-956-0
CAS number: 67953-76-8
The substance is of low short-term toxicity to fish with key values of
96 h LC50 195 mg/L tested with HEDP-H on Oncoryhnchus
mykiss (ABC, 1979) and 96 h LC50 2180 mg/L tested with
HEDP-H on Cyprinodon variegatus (EG&G, 1976).
A 14 d NOEC value of 60 mg/L (as
active acid) has been determined for the effects of HEDP-H on the
altered behaviour and loss of equilibrium of the freshwater fish Salmo
gairdneri (now known as Oncorhynchus mykiss) (ABC, 1979). There
are no true long-term toxicity to fish studies with the registration
substance and this endpoint has been waived.
The registration substance is of low short-term toxicity to
invertebrates with key values of 48 h EC50 527 mg/L with D.
magna as HEDP-H (Monsanto, 1981) and a 96 h LC50 1770
mg/L with P. pugio as HEDP-H (EG&G, 1976).
A 28 day NOEC value of 6.75 mg/L
has been determined for the effects of HEDP-H on adult mortality and
offspring production of the freshwater invertebrate Daphnia magna (Monsanto,
The algal inhibition study has been waived on the basis that:
In accordance with Section 2 of REACH Annex
XI, the study does not need to be conducted because an assessment of
the toxicity to aquatic algae and cyanobacteria is technically not
possible due to substances complexing properties of essential
nutrients present in the test media.
A weight of evidence approach is used for aquatic microbial inhibition
studies. The available data supports a conclusion of an EC0
value of at least 200 mg active acid/L in aerobic and anaerobic
microorganisms under prolonged exposure in STP simulation tests.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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