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EC number: 267-956-0
CAS number: 67953-76-8
The absorbed radioactivity was mostly eliminated via faeces (0.082 %),
while a minor part was eliminated via urine (0.025 %). Elimination via
faeces was similar in both collection periods (0 - 24 h and 24 - 48 h),
while elimination via urine was predominantly found in the first
collection period. After 48 h a mean of 0.339 % of the applied
radioactivity could be found in the remaining carcass.
Cutaneous absorption and elimination of sodium HEDP was determined in
male rats. The measurements were performed with 14C labelled
CA 2. The radioactive substance was applied as a 1 % solution to the
shaved back skin of rats. Absorption and elimination was measured after
48 h. After this time, 0.46 % of the applied radioactivity was absorbed.
This shows that sodium HEDP is absorbed poorly. The main route of
elimination was via faeces. Most of the absorbed amount (0.34 %) could
be found in the remaining carcass (excluding the skin of the application
area) at the end of the test. This may suggest a delayed elimination and
probably an accumulation in the bones.
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