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EC number: 265-191-7
CAS number: 64742-88-7
A complex combination of hydrocarbons obtained from the distillation of crude oil or natural gasoline. It consists predominantly of saturated hydrocarbons having carbon numbers predominantly in the range of C9 through C12 and boiling in the range of approximately 140°C to 220°C (284°F to 428°F).
mortalities in the study.
Clinical signs were:
discharge in 1/10 animals - cleared by day 2
ocular discharge in 1/10 animals - cleared by day 2
Loose stools in 2/10 animals - cleared by day 2
Lethargy in 1/10 animals - cleared by day 2
Stained coat in 10/10 animals - cleared by day 4
Alopecia in 10/10 animals to 9/10 animals day 14.
All animals gained weight during the study.
There were no abnormalities at necropsy.
In an acute oral toxicity study, groups of
fasted, young adult, Sprague Dawley rats, five male and five female,
were given a single oral dose of undiluted thermocracked kerosine at a
dose of 5000 mg/kg bw and observed for 14 days.
There were no treatment related mortalities.
All of the study animals exhibited one or more of the following clinical
signs: nasal discharge, ocular discharge, abnormal stools, lethargy,
stained coat, and alopecia. All animals gained weight during study
period. At necropsy, one of the ten animals exhibited visual lesions,
the remaining nine showed signs of alopecia in the inguinal and/or
perineal regions. The oral LD50 was determined to be greater than 5000
mg/kg in males and females.
This study received a Klimisch score of 1
and is classified as reliable without restriction because it was carried
out according to EPA OTS 798.1175 and equivalent or similar to OECD TG
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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