Adenosine 5'-(trihydrogen diphosphate), monopotassium salt

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Administrative data

Endpoint:

relative self-ignition temperature (solids)

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

other:

Justification for type of information:

See further information in the cross-ref.

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

self-heating substances / mixtures

Type of information:

experimental study

Adequacy of study:

key study

Study period:

7-11 January 2021

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.4 (Test method for self-heating substances)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Specific details on test material used for the study:

Batch No.: 37779100
Storage Conditions: Refrigerator (approx. 2 °C to 8 °C)

Key result

Test procedure:

100 mm sample cube at 140°C

Max. temp. reached:

140

Induction time (h):

36

Result:

negative outcome (no effect observed)

Remarks:

The temperature in the centre of the sample using a 100 mm cube sample (weighed mass: 717.22 g) didn’t exceed the oven temperature of 140 °C within 36 h.

Due to the negative result in the 100 mm cube sample at an oven temperature of 140 °C further tests were not necessary.

Interpretation of results:

not classified based on GHS criteria

Conclusions:

The test item Adenosine 5'-diphosphate monopotassium salt (dried) (CAS no. 70285-70-0) indicated no self-heating at atmospheric pressure in the 100 mm cube sample at a temperature of 140 °C.
According to the results of the tests on the self-ignition in the Bowes-Cameron-Cage Test
(UN Test N.4) the test item is classified as follows:
UN Transport Regulation: The test item should not be classified as self-heating substance in Class 4, Division 4.2 according to the UN Transport Regulation.
GHS / CLP Regulation (EC) No 1272/2008 Annex I: 2.11: The test item should not be classified as self-heating substance according to GHS or Regulation (EC) No 1272/2008 (CLP-Regulation) Annex I: 2.11, respectively.

Executive summary:

The test item Adenosine 5'-diphosphate monopotassium salt (dried) (CAS no. 70285-70-0) indicated no self-heating at atmospheric pressure in the 100 mm cube sample at a temperature of 140 °C.
According to the results of the tests on the self-ignition in the Bowes-Cameron-Cage Test
(UN Test N.4) the test item is classified as follows:
UN Transport Regulation: The test item should not be classified as self-heating substance in Class 4, Division 4.2 according to the UN Transport Regulation.
GHS / CLP Regulation (EC) No 1272/2008 Annex I: 2.11: The test item should not be classified as self-heating substance according to GHS or Regulation (EC) No 1272/2008 (CLP-Regulation) Annex I: 2.11, respectively.