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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
flash point of flammable liquids
Data waiving:
study technically not feasible
Justification for data waiving:
the study does not need to be conducted because the flash point is only relevant to liquids and low melting point solids
Cross-reference
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
26 - 30 November 2020
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Version / remarks:
1998
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
EC No. 440/2008
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
1995
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
differential scanning calorimetry
Specific details on test material used for the study:
Batch No.: 37779100
Storage Conditions: Refrigerator (approx. 2 °C to 8 °C)
Key result
Atm. press.:
ca. 1 017 hPa
Decomposition:
yes
Decomp. temp.:
ca. 130 °C

During the heating phase a small endothermic effect was observed starting at a temperature of 190 °C, which was directly followed by a sharp exothermic effect starting at a temperature of 210 °C. The average energy of the exothermic effect was -200 J/g. A second small endothermic effect was observed directly after the exothermic effect starting at a temperature of 220 °C. During the test the test item decomposed and swelled out of the crucible. Due to this result  the test item has no melting point up to its decomposition starting at approx. 130 °C.

Measurement
No.

Sample weight / mg

Onset of Effect / °C

Range of effect / °C

Weight loss / mg

Atmospheric pressure / hPa

PN20579

9.04

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190 – 200 (endo)
210 – 220 (exo)
220 – 230 (endo)

2.93

1016.5

PN20580

11.17

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---
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190 – 200 (endo)
210 – 220 (exo)
220 – 230 (endo)

3.01

1016.5
Conclusions:
The test item Adenosine 5'-diphosphate monopotassium salt (dried) (CAS no. 70285-70-0) has no melting point up to its decomposition starting at approx. 130 °C at atmospheric pressure (1017 hPa) determined by Differential Scanning Calorimetry (DSC) according to Regulation (EC) No 440/2008 Method A.1. and OECD Test Guideline 102 (1995).
Executive summary:

The test item Adenosine 5'-diphosphate monopotassium salt (dried) (CAS no. 70285-70-0) has no melting point up to its decomposition starting at approx. 130 °C at atmospheric pressure (1017 hPa) determined by Differential Scanning Calorimetry (DSC) according to Regulation (EC) No 440/2008 Method A.1. and OECD Test Guideline 102 (1995).

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion