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Short-term toxicity to fish

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Description of key information

The short-term toxicity of the substance to fish was determined in a study in accordance with OECD TG 203. In this study the 96-h LC50 value is 38 mg/L (measured concentration).

Key value for chemical safety assessment

LC50 for freshwater fish:
38 mg/L

Additional information

The short-term toxicity of the substance to fish was determined in a study in accordance with OECD TG 203 and in compliance with GLP criteria (Brixham Environmental Laboratory, 2009). In this study Oncorhynchus mykiss (7 per concentration) were exposed to nominal concentrations of 15, 30, 60, 120 and 240 mg/L test substance and a dilution water control for 96 hours under static conditions. Test concentrations were analytical verified. Measured concentrations were 12, 25, 59, 140 and 500 mg/L (arithmic mean). The high measured concentration for the nominal 240 mg/L solution was attributed to the presence of colourless, oily globules in the test solution. Observations for mortalities and symptoms of toxicity were made at 24, 48, 72 and 96 hours after exposure. Symptoms of toxicity were also recorded at 3 hours. At test concentrations of 12 and 25 mg/L no mortalities were observed and symptoms of toxicity were minimal and reversible. At all higher concentrations cumulative mortalities were 100%. Before death general symptoms of toxicity were surfacing, loss of balance, and dark discolouration. Based on the available data, the 96-h LC50 value is 38 mg/L (measured concentration).