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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data from handbook.

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Kirk-Othmer Encyclopedia of chemical technology; Blood, Coagulants and Anticoagulants to Cardiovascular agents
Author:
Kirk-Othmer
Bibliographic source:
3rd edition, Vol. 4, Wiley-Interscience, New York, pg. 765
Reference Type:
review article or handbook
Title:
Ullmann's Encyclopedia of Industrial Chemistry, Volume A6, Ceramics to Chlorohydrins
Year:
1986
Bibliographic source:
VCH, pg. 559 564

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Phenyl chloroformate
EC Number:
217-547-8
EC Name:
Phenyl chloroformate
Cas Number:
1885-14-9
Molecular formula:
C7H5ClO2
IUPAC Name:
phenyl chloroformate
Details on test material:
Molecular weight: 156.57
Molecular formula: C7H5ClO2

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 581 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
According to Ullmann's Encyclopedia of Industrial Chemistry and Kirk-Othmer Encyclopedia of Chemical Tocixology the oral LD50 of Phenyl chloroformate to rats is 1581 mg/kg.