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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Consensus model in Test v4.2.1
Model prediction report is attached in IUCLID
GLP compliance:
no
Test type:
other: QSAR predicition

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Purity: Not applicable
- Smiles: OC1C{P-}(O)C{P-}(O)C{P-}(O)C{P+}(O)C{P-}1O

Test animals

Species:
rat

Results and discussion

Effect levels
Key result
Dose descriptor:
LD50
Effect level:
19 483.68 mg/kg bw
Remarks on result:
other: QSAR predicted value

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
LD50 (rat): 19483.68 mg/kg
Executive summary:

The consensus model in Times v4.2 was used to predict the acute toxicity to rats. The oral LD50 in rats was predicted to be 19483.68 mg/kg. Additional supporting documentation is provided in the prediction report attached in IUCLID.