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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Qualifier:
no guideline available
Principles of method if other than guideline:
Consensus model in Test v4.2
Model prediction report is attached in IUCLID
GLP compliance:
no
Specific details on test material used for the study:
SMILES: OC1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
Test organisms (species):
Pimephales promelas
Test type:
other: QSAR
Total exposure duration:
96 h
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
5 424.33 mg/L
Remarks on result:
other: QSAR predicted value
Validity criteria fulfilled:
yes
Conclusions:
96-hour LC50 (fathead minnow): 5424.33 mg/L
Executive summary:

The consensus model in Times v4.2 was used to predict the acute toxicity to Pimephales promelas (fathead minnow). The 96 -hour LC50 in fathead minnow was predicted to be 5424.33 mg/L. Additional supporting documentation is provided in the prediction report attached in IUCLID.

Description of key information

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
5 424.33 mg/L

Additional information