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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Link to relevant study record(s)

Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Reference:
Composition 0
Qualifier:
no guideline available
Principles of method if other than guideline:
Neutral Organic Baseline Toxicity for Green Algae 72-h EC50 (For compounds related to monosaccharides)
Model prediction report is attached in IUCLID
GLP compliance:
no
Test material information:
Composition 1
Specific details on test material used for the study:
SMILES: OC1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O
Test organisms (species):
other: green algae
Test type:
other: QSAR prediction
Total exposure duration:
72 h
Key result
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
> 36 600 mg/L
Remarks on result:
other: QSAR predicted value
Validity criteria fulfilled:
yes
Conclusions:
72-hour EC50 (green algae): >36600 mg/L
Executive summary:

The Neutral Organic Baseline Toxicity for Green Algae 72-h EC50 model was used to predict the acute toxicity to green algae. The 72-hour EC50 in green algae was predicted to be >36600 mg/L. Additional supporting documentation is provided in the prediction report attached in IUCLID.

Description of key information

Key value for chemical safety assessment

EC50/LC50 for freshwater algae:
36 600 mg/L

Additional information