Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2007
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Well documented report of guideline study conducted according to GLP.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2007
Report Date:
2007

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient)
Deviations:
yes
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material: ATBS
- Physical state: white powder
- Analytical purity: 99.4 %
- Lot/batch No.: 061202
- Expiration date of the lot/batch: 30 june 2007
- Storage condition of test material: Room temperature in the dark
- Other: Date received: 18 January 2007

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-3.7
Temp.:
20 °C
pH:
> 1 - < 7

Applicant's summary and conclusion

Conclusions:
The partition coefficient of ATBS was estimated to be less than 0.0002 (equivalent log10Pow < -3.7)