Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
March 1993
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study was done under GLP and is valid, however the analysis is questionable

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1993
Report Date:
1993

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Method C2 of 84/449/EEC OECD Guideline 202
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
88% pure according to CoA

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
no
Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: none

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h

Test conditions

Hardness:
211 mg CaCO3/L
Test temperature:
17.5-19.5
pH:
7.6-8.4
Dissolved oxygen:
96-100% ASV
Nominal and measured concentrations:
nominal: 0, 0.75, 1.5, 3, 6, 12 mg/L
Reference substance (positive control):
no

Results and discussion

Effect concentrationsopen allclose all
Duration:
24 h
Dose descriptor:
EC50
Effect conc.:
2.69 mg/L
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
2.06 mg/L
Duration:
48 h
Dose descriptor:
NOEC
Effect conc.:
0.743 mg/L
Details on results:
%Concentration loss over test: 0 ... 99

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
Study is valid Ec50 was determined to be 2.06 mg/L